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Researcher

Fatiha Chandad

Université Laval

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SEP 3, 2026 · JOURNAL ARTICLE

Metabolic-microbial crosstalk drives inflammasome activation: fasn and palmitoylation mediate palmitate-Porphyromonas gingivalis synergy in macrophage-like cells

Scientific Reports

In vitro mechanistic study in cell culture identifying a potential metabolic-microbial interaction pathway; lacks clinical validation, animal models, or hard endpoints needed to guide practice.

Hypothesis-GeneratingMégane St-Georges Vanessa P. Houde Fatiha Chandad

Study details

DesignIn vitro experimental study using cell cult…

InterventionPalmitate combined with P. gingivalis or TL…

ComparatorPalmitate or P. gingivalis alone; untreated…

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