AUG 19, 2026 · JOURNAL ARTICLE
Genetic Engineering of Tumor‐Infiltrating Lymphocytes ( TIL ) via a T‐Editor Platform to Enhance Anti‐Tumor Activity
Cancer Science
Early-stage mechanistic work demonstrating proof-of-concept for a gene-editing platform in preclinical and PDX models, without human clinical efficacy data or direct comparison to standard TIL therapy.
Study details
DesignPreclinical proof-of-concept and patient-de…
InterventionT-Editor platform with cytosine base editin…
ComparatorNon-engineered control TIL and Cas9-knockou…