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Yasser Iturria-Medina

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada; Ludmer Centre for Neuroinf

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AUG 3, 2026 · JOURNAL ARTICLE

Quantitative susceptibility mapping in neurodegenerative diseases: An umbrella review of iron-related biomarkers and mechanisms.

Magnetic Resonance Imaging

An umbrella review of 15 systematic reviews and meta-analyses confirming QSM as a sensitive biomarker for iron quantification across neurodegenerative diseases, but methodological quality is low and findings require cautious interpretation.

Important Confirmatory EvidenceBiomarkers Alzheimer Disease Neuroimaging

Reported

Number of systematic reviews incl…15

Methodological quality rating (Lo…13/15

Corrected Covered Area overlap5.42%

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