JUN 29, 2026 · JOURNAL ARTICLE
Oral Microbiome and Its Emerging Role in Alzheimer\'s Disease: A Comprehensive Review
Journal of Acute Care Trauma and Emergency Medicine
A narrative review synthesizing mechanistic and associational evidence from animal models, in vitro studies, and observational human data, identifying oral dysbiosis as a plausible but unproven contributor to Alzheimer's disease pathogenesis without definitive human causation or intervention trials.
Reported
Estimated global AD prevalence~55 million people
Oral microbiome species count>700 species
Literature search periodJanuary 2000–December 2024