SEP 9, 2026 · JOURNAL ARTICLE
TRIM21-dependent ubiquitination of MCCase induced by hsa_circ_0009061 drives H3K36 crotonylation to suppress epithelial ovarian cancer progression through regulating glycolysis
Communications Biology
Mechanistic cell and animal study proposing a circRNA-protein-histone pathway in ovarian cancer; no clinical trial data, human efficacy endpoints, or comparison to standard therapy reported.
Study details
DesignMechanistic in vitro and in vivo patient-de…
InterventionAAV2/8 therapy targeting hsa_circ_0009061;…