AUG 14, 2026 · JOURNAL ARTICLE
Targeting SLC6A14-mediated nutrient competition reverses an immunosuppressive metabolic niche in pancreatic cancer
Experimental Hematology and Oncology
Preclinical mechanistic study with in vitro and in vivo experiments identifying a putative target and lead inhibitor, lacking clinical efficacy or safety data in humans.
Reported
Target identification methodVirtual screening of one million-compound l…
Lead inhibitors identifiedTwo target-specific inhibitors identified;…
Mechanism of STOCK1N-75990Competitively blocks amino acid binding, in…