AUG 19, 2026 · JOURNAL ARTICLE
Anxiety and Depression Traits Are Moderated by a Sex-Dependent Genetic Interaction Between 5-HTTLPR and BDNF
Brain Sciences
Single-centre community sample with modest subgroup sizes after stratification, exploratory three-way interaction analysis, and surrogate endpoints (self-reported symptoms); authors acknowledge need for replication in larger cohorts.
Reported
Sample size271
Primary analysis methodthree-way factorial ANCOVA