Disease

Early Alzheimer's Disease

2 developments in the corpus

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AUG 14, 2026 · PHASE 2 TRIAL

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

ClinicalTrials.gov

This is an active Phase 2 interventional trial registration with no posted results; it describes a planned study of a novel tau-targeting agent in early Alzheimer's disease with surrogate neuroimaging endpoints.

PreliminaryNCT07033494 Early Alzheimer's Disease Merck Sharp & Dohme

Reported

Planned enrollment340

PhasePhase 2

Primary outcome measure 1Change from Baseline in Tau PET SUVr, Basel…

AUG 10, 2026 · PHASE 2 TRIAL

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

ClinicalTrials.gov

Phase 2 trial with cognitive endpoint in early Alzheimer's disease; results not yet reported in this registry record, so no efficacy or safety data can be evaluated.

PreliminaryCognition Therapeutics Early Alzheimer's Disease NCT05531656

Reported

Planned enrollment540

PhasePhase 2

Primary outcome measureChange from baseline in Clinical Dementia R…