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Peyton V. Warp

University of Miami

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AUG 17, 2026 · REVIEW

Vitiligo and Skin Cancer Risk: A Systematic Review and Meta‐Analysis With Subtype and Phototherapy Stratification

Jeadv Clinical Practice

Rigorous systematic review and meta-analysis of 14 studies with 454,307 vitiligo patients demonstrating statistically significant inverse association with squamous cell carcinoma and consistent inverse trends for melanoma and overall NMSC, though with wide confidence intervals.

Strong EvidencePeyton V. Warp JJ Jimenez Simonetta I. Gaumond

Reported

Melanoma odds ratio0.43

Melanoma 95% CI0.16–1.13

Squamous cell carcinoma odds ratio0.76

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