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Xingya Wang

Zhejiang Chinese Medical University

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AUG 10, 2026 · JOURNAL ARTICLE

Kaempferol CounteractsObesity and Impairs Adipogenesisby Suppressing PI3K/AKT/GSK3β-Mediated Mitotic Clonal Expansionand Attenuating Adipose Tissue Fibrosis

Journal of Agricultural and Food Chemistry

Mechanistic study in cell culture and diet-induced obesity model with surrogate endpoints; establishes a biological pathway but lacks human evidence and hard clinical outcomes needed to guide practice.

Hypothesis-GeneratingJingsa Zhang Yilu Shou Metabolism, Diabetes, and Cancer

Study details

DesignIn vitro (cell culture) and in vivo (diet-i…

InterventionKaempferol (dietary flavonoid)

ComparatorControl (untreated preadipocytes and standa…

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