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Researcher

Nolan M Dvorak

Developmental Neurogenetics Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX, USA.

1 development in the corpus

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JUN 22, 2026

mTORC2-Nav1.2 signaling drives early hyperexcitability in Alzheimer's disease mouse model.

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Mouse model identifies mTORC2-Nav1.2 mechanism underlying hyperexcitability in Alzheimer's disease, but lacks clinical translation or quantified intervention effect.

PreliminaryAlzheimer Disease Disease Models, Animal Nolan M Dvorak

Study details

DesignPreclinical mechanistic study

InterventionGenetic deletion of mTOR complex 2 (mTORC2)

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