AUG 14, 2026 · REVIEW
Anti‐Amphiphysin Stiff‐Person Spectrum Disorders: A Systematic Review and Case Series Featuring an Unusual Isolated Upper‐Limb Presentation
Movement Disorders Clinical Practice
A systematic review with pooled case series analysis (n=64) describing clinical features, outcomes, and treatment responses in anti-amphiphysin SPSD, but lacking a comparator group and relying on retrospective heterogeneous case data without controlled design.
Reported
Sample size (pooled cohort)64
Lower limb involvement37/45 = 82.2%
Upper limb involvement57.8%