AUG 5, 2026 · JOURNAL ARTICLE
Clinical application value of metagenomic next-generation sequencing in children with fever of unknown origin
Frontiers in Pediatrics
Single-center retrospective analysis of 41 children with uncontrolled selection bias (only tested after conventional failure), no control arm, and equivalence to standard testing rather than superiority; generates descriptive data warranting prospective validation.
Reported
Sample size41
Patients with pathogen detected b…20
mNGS microbial isolates identified30