SEP 5, 2026 · JOURNAL ARTICLE
PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathway
Nature Communications
A mechanistically sound study combining genetic and pharmacological approaches in mouse and human models, demonstrating PRMT7 inhibition enhances CD8+ T cell function, but limited by single tumor model and lack of phase-controlled clinical trial.
Reported
MechanismPRMT7 associates with RelA and restricts Re…