Brain Metastases

SEP 9, 2026 · PHASE 2 TRIAL

Repotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain Metastasis

ClinicalTrials.gov

This is a recruiting Phase 2 trial with no results posted; it describes a planned study of repotrectinib in a specific population but carries no efficacy or safety data yet.

SEP 9, 2026 · PHASE 2 TRIAL

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

ClinicalTrials.gov

This is an active Phase 2 interventional trial with no results posted; the registry record describes planned enrollment and primary outcome measures only, representing early-stage evaluation of a novel radiosensitizer in brain metastases.

AUG 14, 2026 · PHASE 2 TRIAL

A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer)

ClinicalTrials.gov

This is a recruiting Phase 2 single-arm trial with no posted results; it represents early-stage investigation of a three-drug combination for brain metastases from NSCLC.