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Rameen Shahid

Regional Medical Center

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AUG 13, 2026 · JOURNAL ARTICLE

Novel Lipoprotein (a) Therapies: A Comprehensive Review

Current Atherosclerosis Reports

A comprehensive narrative review synthesizing phase 1–3 trial data, regulatory updates, and pipeline information to inform clinical and research practice regarding emerging Lp(a) therapies.

Expert GuidanceUgochukwu Ebubechukwu Onyinye Ugoala Rameen Shahid

Reported

Pelacarsen Lp(a) reductionabout 80%

Olpasiran Lp(a) reduction> 95%

Lepodisiran Lp(a) reduction93.9%

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