AUG 19, 2026 · JOURNAL ARTICLE
Epigenetic priming and locus-specific demethylation enhance cell-death susceptibility in liver cancer
Molecules and Cells
Mechanistic proof-of-concept in cell lines using CRISPR-dCas9 epigenetic editing, without in vivo validation or clinical outcomes, raising a therapeutic hypothesis rather than establishing efficacy.
Reported
5-AZA treatment dose2 μM