JUN 26, 2026 · JOURNAL ARTICLE
Silencing Triglycerides: The Clinical Impact of Plozasiran and apoC-III Inhibition in Severe Hypertriglyceridemia
Journal of Cardiovascular Pharmacology
Phase III trial demonstrates robust triglyceride reduction and favorable safety in a specific high-risk population, but lacks hard clinical outcome data and generalizability beyond familial chylomicronemia syndrome.
Study details
DesignPhase III randomized controlled trial (PALI…
InterventionPlozasiran (APOC3-targeting small interferi…