AUG 24, 2026 · JOURNAL ARTICLE
Assessment of the safety and efficacy of sodium pentaborate pentahydrate in individuals with overweight and obesity: a randomized, double-blind, placebo-controlled, phase 1/2 dose-finding trial.
Adipocyte
Phase 1/2 dose-finding trial with modest sample size (116 completers) and short 12-week duration showing exploratory efficacy signals without major safety concerns, but requiring confirmation in phase 3 trials before clinical application.
Reported
Sample size (completers)116
Sample size (randomized)177
Body weight change, 1,000 mg group−3.1 kg