JUL 28, 2026 · JOURNAL ARTICLE
Rv2140c is targeted by follicular helper T cells in M.tuberculosis exposed γ Interferon Release Assay negative populations in Uganda and South Africa 2299672
The Journal of Immunology
This is an exploratory mechanistic study using novel discovery platforms in small populations that identifies a candidate antigen and proposes a new protective mechanism, but lacks clinical validation or outcome data to confirm the hypothesis.
Study details
DesignCross-sectional comparative study using TCR…
InterventionTCR sequencing, antigen discovery, and immu…
ComparatorIGRA-negative resisters versus IGRA-positiv…