SEP 2, 2026 · JOURNAL ARTICLE
Gut microbial H2S promotes metabolic dysfunction in mice via hepatic PPARα suppression
The Isme Journal
Mechanistic mouse model study with human metagenomic association but no human intervention trial; demonstrates pathway mechanism in rodents without clinical outcome data or human causal evidence.
Study details
DesignExperimental mouse models integrated with h…
InterventionAdministration of H2S-producing Desulfovibr…
ComparatorControl groups in mice; specific comparator…