AUG 17, 2026 · JOURNAL ARTICLE
Fructose directly remodels the translocase of the outer membrane to impair oxidative phosphorylation in podocytes
Signal Transduction and Targeted Therapy
This is a mechanistic study using in vitro biochemistry and cell/animal models to propose a novel pathway; it raises a question about fructose's direct effects on mitochondria rather than providing clinical evidence ready to guide practice.
Study details
DesignPreclinical mechanistic study combining in…
InterventionFructose exposure and disruption of fructos…
ComparatorControl (untreated) or standard fructose ex…