AUG 11, 2026 · JOURNAL ARTICLE
Preclinical evaluation of PSMA-targeted ultrasound contrast agents in an orthotopic model of prostate cancer in rabbits.
Bioactive Materials
First-in-vivo preclinical study of a novel PSMA-targeted nanobubble contrast agent in an orthotopic rabbit model, demonstrating proof-of-concept with exploratory endpoints constrained by small cohort size and non-specific histologic validation.
Reported
Peak intensity ratio (tumor core,…1.60-fold
Peak intensity ratio (tumor rim,…1.50-fold
Mean transit time ratio (PSMA-NB…4.20 to 5.40-fold