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Zhiming Lu

Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, China.

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AUG 15, 2026 · JOURNAL ARTICLE

Therapeutic potential and underlying mechanisms of engineered young plasma-derived exosomes in Alzheimer's disease.

Bioactive Materials

This is a preclinical mechanistic study in transgenic AD mouse models using engineered exosomes; it demonstrates a proposed therapeutic pathway but lacks clinical translation, human data, or rigorous comparison to establish practice-changing or even strong evidence.

Hypothesis-GeneratingZhiming Lu Zhikang Cui Yuanquan Si

Study details

DesignPreclinical mechanistic study in transgenic…

InterventionRVG-engineered young plasma-derived exosome…

ComparatorYoung plasma-derived exosomes (unengineered…

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