AUG 5, 2026 · JOURNAL ARTICLE
Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities.
Journal of Affective Disorders
A large retrospective cohort study identifying novel proteomic markers associated with dementia risk in comorbid T2DM and MDD, with clear statistical associations but requiring prospective validation and mechanistic confirmation.
Reported
Sample size15765
Comorbid T2DM + MDD subgroup721
MDD only subgroup1230