AUG 31, 2026 · JOURNAL ARTICLE
Temporal trends and mortality associated with difficult-to-treat resistance in bloodstream gram-negative bacilli: a retrospective cohort study in Southern Saudi Arabia
Frontiers in Cellular and Infection Microbiology
Rigorous retrospective cohort study with large sample, multivariate adjustment, and hard clinical outcome (30-day mortality) directly linked to a well-defined resistance phenotype across two major gram-negative pathogen classes.
Reported
Sample size (total isolate-episod…2027
Sample size (patients)1695
Enterobacterales proportion73.4%