AUG 18, 2026 · JOURNAL ARTICLE
Factors associated with grade ≥2 acute radiation dermatitis after adjuvant radiotherapy in breast cancer patients with immediate breast reconstruction: a single-center study using penalized regression
Frontiers in Oncology
Single-center retrospective study with small sample (n=61), high event rate (72%), and hypothesis-generating findings requiring validation in larger cohorts, limiting confidence in generalizability.
Reported
Grade ≥2 acute RD incidence72.1% (44/61)
Odds ratio for age (per 10 years)2.30
95% CI for age effect1.11–5.87