AUG 11, 2026 · JOURNAL ARTICLE
Noninvasive prediction of classic EGFR-activating mutations in non-small cell lung cancer using a combined spectral computed tomography model: an auxiliary tool for preoperative stratification of candidates for EGFR-TKI therapy
BMC Pulmonary Medicine
A single-centre retrospective study with internal validation showing a diagnostic model for EGFR mutation prediction; the result is clear and clinically relevant but limited by retrospective design, modest sample size, and lack of external validation.
Reported
AUC (combined model)0.805
AUC (clinical-conventional CT mod…0.642
P-value (model comparison)< 0.001