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JUL 23, 2026 · JOURNAL ARTICLE

Cognitive neurodynamics of affective disorders.

Cognitive Neurodynamics

A computational modelling study proposing that affective disorders reflect distinct dynamical regimes of a single homeostatic controller; proof-of-principle simulations generate testable predictions but provide no empirical validation in human subjects.

Hypothesis-GeneratingAffective Disorders Luigi Manfredi Xinpeng Liu

Study details

DesignComputational modelling and mathematical si…

InterventionMathematical modelling of opponent-process…

ComparatorModel behaviour under 'healthy' parameters…

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