SEP 9, 2026 · PREPRINT
Are You Learning Biological Signal or Shortcuts? Auditing and Mitigating Bias in Protein-Protein Interaction Datasets
arXiv
A methodological audit and tool development study identifying and proposing mitigation strategies for biases in PPI datasets; important for ML validation but lacks empirical validation of the proposed pipeline's effectiveness on downstream prediction tasks.
Study details
DesignMethodological audit with computational too…
InterventionOptimization-based dataset splitting and ne…
ComparatorStandard random data splitting and existing…