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Mechanistic study in knockout bacteria and mouse models identifying a QS gene's role in virulence; lacks clinical outcome data and remains exploratory regarding therapeutic translation.
A narrative review synthesizing evidence on NGS applications in melioidosis diagnosis, epidemiology, and resistance surveillance, offering clinical and laboratory guidance without presenting new empirical data or a primary study result.
Single case report of an uncommon clinical presentation; documents diagnosis and management but lacks comparative data, control group, or outcome statistics needed for stronger evidence grades.
A small retrospective case series (4 cases) combined with descriptive literature review synthesis; generates clinical insights for a rare disease but lacks control groups, prospective design, or quantified interventional outcomes to support definitive guidance.
International Journal for Multidisciplinary Research
Single-centre descriptive antibiogram from a 6-month observational study with 102 patients; no comparator, no hypothesis test, and no clinical outcome data—useful for local empirical guidance but not evidence of efficacy or clinical impact.