SEP 8, 2026 · JOURNAL ARTICLE
N-terminal thrombospondin-1 enhances muscle function and tissue-specific metabolic adaptation in response to exercise and cold exposure
Experimental & Molecular Medicine
A mechanistic study combining mouse models and human correlation data showing N-TSP1 enhances muscle function and metabolic markers, but lacks controlled human trials and relies on surrogate endpoints and observational human data.
Study details
DesignMechanistic experimental study in mouse mod…
InterventionN-TSP1 (N-terminal thrombospondin-1) admini…
ComparatorControl (untreated) mice; no comparator in…