SEP 5, 2026 · JOURNAL ARTICLE
Meningioma enlargement associated with luteinizing hormone-releasing hormone agonist therapy: two cases and supporting in vitro evidence
Brain Tumor Pathology
Two case reports with supporting ex vivo evidence raise a mechanistic hypothesis about LHRH agonists and meningioma growth, but lack controlled comparison, prospective data, or clinical outcome quantification to establish causation or clinical risk.
Reported
Case 1 tumor enlargement duration…26 months
Case 2 radiographic stability dur…6 years
Case 1 age67 years