AUG 12, 2026 · JOURNAL ARTICLE
Azoreductase-ResponsiveNIR Fluorescent Self-AssembledProbe for Hypoxia Imaging of Tumors, Hindlimb Ischemia, and UlcerativeColitis
Analytical Chemistry
This is a preclinical mechanistic study describing development and proof-of-concept validation of a novel imaging probe in cell culture and animal models; it does not test clinical utility, efficacy, or safety in humans.
Reported
Fluorescence enhancement p-valueP < 0.01
Fold increase in NIR signal (LLC…3.5-fold
Linear correlation (hindlimb isch…R² > 0.9