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Tatsuya Fukuda

Ohkubo Hospital

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SEP 9, 2026 · JOURNAL ARTICLE

Accumulation and Time-Dependent Changes in Unfavorable Eating Behaviors and the Risk of Incident Metabolic Dysfunction-Associated and Alcohol-Related/Associated Steatotic Liver Disease: A Retrospective Cohort Study

Nutrients

Large, well-designed retrospective cohort study with 29,889 participants, 4,829 incident events, and 115,088 person-years of follow-up demonstrating dose-dependent associations between cumulative unfavorable eating behaviors and incident liver disease with consistent effect estimates across multiple analytical approaches.

Strong EvidenceTatsuya Fukuda Koshiro Monzen Makoto Tanaka

Reported

Sample size29889

Incident events (MASLD/MetALD)4829

Total person-years of follow-up115088

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