JOURNAL ARTICLE
Britanin improved high-fat diet-induced obesity by regulating the MAPK signaling pathway.
Pakistan Journal of Pharmaceutical Sciences
Single-center animal study with mechanistic validation but no human data, uncontrolled design, and surrogate endpoints only; insufficient for clinical guidance despite sound experimental approach.
Reported
Body weight reduction (high-fat d…18%
Serum triglyceride change-45%, p<0.001
Serum total cholesterol change-37%, p<0.001