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Shaza Asif

University of Ottawa

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SEP 3, 2026 · JOURNAL ARTICLE

Sex- and Ketogenesis-Dependent Effects of Intermittent Fasting on Diet-Induced Fatty Liver Disease

Diabetes

Mechanistic animal study identifying sex-dependent pathways in intermittent fasting; raises questions about human applicability and sex-specific therapeutic design rather than establishing clinical evidence.

Hypothesis-GeneratingShaza Asif Yena Oh Hyejin Lee

Study details

DesignPreclinical mechanistic study in male and f…

InterventionIntermittent fasting; Hmgcs2 expression kno…

ComparatorControl mice without IF and/or without Hmgc…

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