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Fotios Dimitriadis

University of Ioannina

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AUG 13, 2026 · JOURNAL ARTICLE

Gemcitabine-Based Bladder Preservation in BCG-Unresponsive High-Risk NMIBC: Evidence, Limitations, and Clinical Positioning

Biomedicines

A narrative review synthesizing evidence for bladder-sparing gemcitabine-based therapies in BCG-unresponsive NMIBC, positioning treatment options within current clinical guidelines and acknowledging limitations of the underlying evidence.

Expert GuidanceFotios Dimitriadis Ilias Giannakodimos Aris Kaltsas

Reported

TAR-200 complete response rate82.4%

TAR-200 median duration of respon…25.8 months

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