SEP 4, 2026 · JOURNAL ARTICLE
Thymoquinone Is Effective in Painful Paclitaxel-Induced Peripheral Neuropathy Without Compromising Anticancer Activity
Biomolecules
Early-stage preclinical and animal study demonstrating analgesic efficacy of thymoquinone in paclitaxel-induced neuropathy, but with limited structural neuroprotection and no human data, requiring confirmation before clinical translation.
Reported
TQ concentration (in vitro)5 μM
PTX dose (in vivo)10 mg/kg, i.v., weekly for 4 weeks
TQ dose (in vivo)5–10 mg/kg/day, oral