AUG 30, 2026 · JOURNAL ARTICLE
Cryptotanshinone inhibits Staphylococcus aureus NdhC via uncompetitive inhibition: Collateral sensitivity in respiratory-deficient SCVs.
Virulence
This is a mechanistic study using in vitro enzymatic assays, molecular docking, and site-directed mutagenesis to characterize cryptotanshinone's inhibition of bacterial NADH dehydrogenase; it raises questions about therapeutic potential rather than demonstrating clinical efficacy.
Reported
Fold increase in bacterial sensit…2-fold