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Advanced Or Metastatic Solid Tumors

1 development in the corpus

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AUG 10, 2026 · PHASE 1 TRIAL

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

ClinicalTrials.gov

First-in-human Phase 1 trial of a novel proteasome inhibitor designed to evaluate safety, tolerability, and preliminary anti-tumor activity; no results are yet reported in this registry record.

PreliminaryAdvanced Or Metastatic Solid Tumors Triple Negative Breast Cancer (TNBC)SHY Therapeutics

Reported

Planned enrollment30

PhasePhase 1

Primary outcome: DLT assessment p…Day 1 through Day 21 of Cycle 1 (21-day cyc…

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