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Melanie Garmon

Inserm

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SEP 3, 2026 · JOURNAL ARTICLE

Additive effects of metformin on glucose homeostasis after metabolic-bariatric surgery in non-obese insulin-deficient diabetic rats

American Journal of Physiology-endocrinology and Metabolism

Preclinical animal study in a non-obese diabetic rat model that raises mechanistic questions about metformin and bariatric surgery combination; not designed to inform human clinical practice.

Hypothesis-GeneratingMelanie Garmon Danielle Bailbe Maude Le Gall

Reported

Metformin dose50 mg/kg/day

Metformin dosing schedule5 days/week for three weeks

Postoperative treatment windowthree weeks after surgery

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