AUG 11, 2026 · JOURNAL ARTICLE
An ICAM1⁺ inflammatory fibroblast state in atrial fibrillation and metabolic-stress-associated atrial remodeling
Biology Direct
Single-centre mechanistic study combining human transcriptomics reanalysis with mouse disease modelling and in vitro fibroblast manipulation; identifies a putative fibroblast state and pathway associations but lacks clinical endpoints and acknowledges need for further work to establish causality and clinical relevance.
Reported
ICAM1⁺ fibroblast prevalence in A…17.3%
AF-like arrhythmia susceptibility…5/8 vs. 0/8
Fisher's exact p-value (arrhythmi…0.0256