AUG 14, 2026 · JOURNAL ARTICLE
Enhancing iNKT cell immunotherapy through the integration of optimized CAR endodomains and iNKT engagers
Nature Communications
Mechanistic and preclinical study demonstrating CAR-iNKT cell engineering and engager design in vitro and in animal models, without clinical efficacy data or human trials.
Study details
DesignPreclinical mechanistic study
InterventionFive different CAR endodomains in iNKT cell…
ComparatorCAR-T cells; FCRL5 CAR-iNKT without engager.