AUG 24, 2026 · JOURNAL ARTICLE
A single nucleotide polymorphism collapses phase variation and drives short-sighted evolution of O-antigen in Salmonella.
Gut Microbes
This is a mechanistic study identifying a single nucleotide polymorphism in a promoter region and demonstrating its effect on O-antigen expression in Salmonella through in vitro and bacterial culture work, without clinical outcome data or human studies.
Reported
Frequency of antigenic conversion…around 5%
Promoter substitution position–34
Nucleotide changeC-to-A