AUG 11, 2026 · JOURNAL ARTICLE
Chemotherapy remains effective in ALK-TKI therapy: a retrospective analysis in ALK-positive advanced NSCLC
BMC Cancer
Retrospective analysis of 109 patients showing statistically significant survival benefits with chemotherapy integration in ALK-positive NSCLC, but limited by observational design, potential confounding, and lack of randomization.
Reported
Sample size109
Median PFS2 (chemotherapy vs. no…29.9 vs. 23.4 months
P-value (PFS2 with vs. without ch…0.039