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Maria Clara Junqueira Teles de Menezes

Faculdade de Medicinada Universidade de São Paulo, São Paulo, Brazil.

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JUN 25, 2026 · JOURNAL ARTICLE

Clinical response after cerebrospinal fluid shunting in complex versus pure idiopathic normal pressure hydrocephalus: A systematic review and meta-analysis.

Clinical Neurology and Neurosurgery

Systematic review and meta-analysis of 19 studies showing low-to-very-low-certainty evidence that complex iNPH has greater uncertainty and possibly lower global shunt response than pure iNPH, but response remains clinically meaningful in both groups.

Important Confirmatory EvidenceMaria Clara Junqueira Teles de Menezes Caio Arruda Maciel Kauã Gabriel Oliveira da Silva

Reported

Global shunt response (complex vs…OR 0.31, 95% CI 0.09–1.10

Urinary improvement (complex vs p…OR 0.85, 95% CI 0.58–1.25

Number of analytical studies incl…19

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