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Emmanuelle Corruble

Inserm

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AUG 1, 2026 · JOURNAL ARTICLE

Prucalopride repurposing: 5-HT4 receptor agonists in anxiety and depression

L Encéphale

This is a perspective article proposing a mechanistic hypothesis about 5-HT4 receptor agonists in mood disorders, supported by preclinical evidence and epidemiological suggestion, but lacking clinical trial data demonstrating efficacy in humans with depression or anxiety.

Hypothesis-GeneratingDenis J. David Indira Mendez-David Emmanuelle Corruble

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