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Toon Braeye

Sciensano, Elsene, Belgium.

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JUL 26, 2026 · JOURNAL ARTICLE

Adapted XBB.1.5 vaccine effectiveness against severe COVID-19 outcomes among immunocompromised persons in 2023-24 in six European countries: a VEBIS-EHR network study.

Expert Review of Vaccines

Multi-country retrospective cohort study with confounder-adjusted hazard ratios and meta-analysis pooling, demonstrating moderate vaccine effectiveness against severe outcomes in a vulnerable population, though protection wanes over time.

Strong EvidenceToon Braeye Vaccine Efficacy Izaak Van Evercooren

Reported

Vaccine effectiveness against hos…52%

95% CI for VE against hospitaliza…41 to 60

Vaccine effectiveness against dea…75%

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