SEP 9, 2026 · JOURNAL ARTICLE
Defining metabolic heterogeneity in polyendocrine metabolic ovarian syndrome based on the MTHFR C677T polymorphism: the potential pathway role of homocysteine
Journal of Ovarian Research
A retrospective, cross-sectional genotyping study proposing a mechanistic pathway (MTHFR genotype → homocysteine → metabolic heterogeneity) without causal evidence; the authors acknowledge exploratory design and explicitly call for prospective validation.
Reported
Sample size213
CC genotype (n)48
CT genotype (n)124